Mammalian circular RNAs result largely from splicing errors
Summary: Ubiquitous in eukaryotes, circular RNAs (circRNAs) comprise a large class of mostly non-coding RNAs produced by back-splicing.Although some circRNAs have demonstrated biochemical activities, whether most circRNAs are functional is unknown.Here, we test the hypothesis Ceiling Light Fixtures that circRNA production primarily results from spl